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产品目录

Aconitase 1/ACO1抗体图片
产品货号:
Z32673
中文名称:
Aconitase 1/ACO1抗体
英文名称:
Anti-Aconitase 1/ACO1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Aconitase 1/ACO1 Antibody
指标别名ACO1;Aconitase;Aconitase 1;aconitase 1;soluble;ACONS;Citrate hydro lyase;Ferritin repressor protein;IRE BP 1;IREB1;IREBP;IREBP1;Iron regulatory protein 1;IRP1
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,ICC/IF
基因名称ACO1
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human Aconitase 1
实际分子量98KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料The protein encoded by this gene is a bifunctional,cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells.When cellular iron levels are high,this protein binds to a 4Fe-4S cluster and functions as an aconitase.Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate.When cellular iron levels are low,the protein binds to iron-responsive elements (IREs),which are stem-loop structures found in the 5' UTR of ferritin mRNA,and in the 3' UTR of transferrin receptor mRNA.When the protein binds to IRE,it results in repression of translation of ferritin mRNA,and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.Alternative splicing results in multiple transcript variants.
Uniprot IDP21399
基因名全称Cytoplasmic aconitate hydratase
推荐稀释比
Western blot (WB) 1:500~2000
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100

相关搜索:Aconitase 1/ACO1抗体Aconitase 1抗体ACO1单抗Anti-Aconitase 1/ACO1 Antibody
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